Loading

Publications

The following is a select list of employee publications and presentations.

Journal Articles

31P{1H} NMR studies of the transesterification polymerization of polyphosphonate oligomers
Bharara, Prakash C.; Branham, Keith E; Byrd, Houston; Dees, Jennifer; Farmer, Brandon; Gray, Gary M.; Myrex, Dustan, R.; and Young-Jin Wright.
European Polymer Journal 2003, Vol. 39, pp. 1105-1115.

In vitro and in vivo degradation studies of a novel linear copolymer of lactide and ethyl phosphate
Branham, Keith E.; Chaubal, Mahesh V.; Dang, Wenbin; English, James P.; Spicer, Eric; Su, Geraldine; and Zhong, Zhao J.
Biomaterials Science Polymer Edition 2003, Vol. 14, pp. 45-61.

31P{1H} NMR studies of dichlorotris(2,4,6-tribromophenoxy)phosphorane, trichlorobis(2,4,6-tribromophenoxy)phosphorane, tetrahloro(2,4,6-tribromophenoxy)phosphorane, and their nonoxidative chlorination reactions with dimethyl phosphonate
Bharara, Prakash C.; Branham, Keith E.; Byrd, Houston; and Gray, Gary M.
Main Group Chemistry 2000, Vol. 3, pp 103-108.

Polycondensation of dimethyl phosphonate with diols: SEC and 31P and 13C NMR spectroscopic studies
Bharara, P.C; Bittinger, R.; Branham, K.E.; Byrd, H.; Farmer, B.; Gray, G.M.; and
Mays, J.W.
Polymer 2000, Vol. 41, pp. 3371-3379.

Reactions of titanocene derivatives with molecular carboxylic acids and copolymers bearing carboxylic acid groups
Branham, K. E.; Cook, R.; Gray, G.M.; Mays, J.W.; Overturf, G.E.; and Sanner, R.D.
Applied Organometallic Chemistry. 1997, Vol. 11, pp.213-227.

Presentations

Transesterification and End Group Chemistry in Acid Terminated Biodegradable Polymers

Branham, Keith E.; Mukherjee, R.; Hall, D.; and Gibson, Presented at the 34th Annual Meeting of the Controlled Release Society. July 9, 2007.

Biodegradable polymers and polymer technologies
Branham, Keith E.
2nd Annual Southeast Tissue Engineering and Biomaterials Workshop. February 11, 2005.

Zero-order, 30-day release of analgesics from coaxial implants
Carraway, K.; Gibson, J.W; Jefferson, R.; Maturi, H.; Meador, S.; and Tipton. A.
Presented at the 28th International Symposium of the Controlled Release Society. June 2001 San Diego, California.

Effect of gamma irradiation on leuprolide acetate release from polylactide implants
Bhardwaj, R.; Gibson, J.W.; Ingallinera, T.S.; Meador, S.K.; Tanglertpaibul, J.; and Tipton, A.J.
Presented at the 27th Symposium on Controlled Release of Bioactive Materials.   July 9-13, 2000.
Paris, France.

Depot delivery of proteins in the new millennium: From microspheres to injectable gels
Cleland, Jeffrey L.; Darling, Susan; Gibson, John; Johnson, Okumu, Franklin W.; OluFumni L.; Sullivan, Stacey; Tipton, Arthur J.; and Zentner, Gaylen M.
Presented at the 6th European Symposium on Controlled Drug Delivery. April 12, 2000.
Noordwijk Aan Zee, the Netherlands.

Synthesis and characterization of linear and branched poly( DL -lactide)s for controlled drug delivery
Branham, Keith E.; Dunn, Richard L.; English, James P.; Frater-Hall, Donna; and Jeffers, Scott.
AAPS Southeastern Regional Meeting. November 14-18, 1999.
New Orleans, Louisiana.

Critical issues in production and manufacturing bioabsorbable polymers for medical / pharmaceutical applications
Branham, Keith E.
Biomaterials Seminar in Atlanta: Bioabsorbable Polymers for Biomedical and Pharmaceutical Applications.   November 15-17, 1999.
Atlanta, Georgia

Biodegradable delivery systems for estradiol: comparison between poly ( DL -lactide) microspheres and the SABER TM delivery system
Gibson, J.W.; Johnson, C.A.; Simon, B.W.; Sullivan, S.A.; Thompson, Jr., D.L.; and Tipton, A.J.
Presented at the 26th International Meeting of The Controlled Release Society.   June 20-25, 1999.
Boston, Massachusetts.

Strategies for scale-up and manufacturing issues
Gibson, J.W.
Invited Lecture at the Postsymposium Workshops of The 26th International Symposium on Controlled Release of Bioactive Materials. June 24-25, 1999.
Boston, Massachusetts

Effect of process variables on the preparation of biodegradable microspheres
Gibson, J.W.; Hudson, B.W.; Moyer, L.M.; and Whitfield, D.R.
Presented at the AAPS Annual Meeting and Exposition. November 15-19, 1998.
San Francisco, California

Development and validation of a stability-indicating method for poly( DL -Lactide) excipients used in Injectable microspheres
Gibson, J.W.; Lawson, S.J.; Martin, C. S.; and Sims, K.R.
Presented at the AAPS Annual Meeting and Exposition. November 15-19, 1998.
San Francisco, California

Pharmacodynamic evaluation of biodegradable Estradiol-17b microspheres and Prostaglandin F2a for the control of Estrus and ovulation in gilts  
Boonyaprakob, U.; Britt, J.; Burns, P.; Cushman, R.; Davis, P.; Gibson, J.; Hedgpeth, V.; and Hudson, B.
Presented at the 25th International Meeting of The Controlled Release Society.   June 21-26, 1998.
Las Vegas, Nevada

Evaluation of a new continuous process for preparation of progesterone and estradiol microspheres: an in vivo pharmacokinetics study.  
Burns, P.J.; Dippert, K.; Ferrell, T.; Gibson, J; Love, D.; Mason, D.; Squires, E.L.; and Tice, T.R.
Poster presented at the 1996 Baltimore Conference on Controlled Release of Bioactive Materials. August 19-20, 1996.
Baltimore, Maryland

Order Polymers

We offer a variety of polymers and sample kits in stock for prompt delivery.

Standard Products

A complete list of Standard Product pharmaceutical grade polymers available from LACTEL.

Custom Polymers

If additional product optimization is required, we can provide developmental input and custom synthesis. A large percentage of our polymer business at DURECT is devoted to the development of polymers with customized characteristics.

Safety Data Sheets

 

The following Safety Data Sheets are saved in a format that can be viewed and printed from Acrobat Reader.
CONTACT US:

LACTEL Absorbable Polymers

2200 Riverchase Center, Suite 501
Birmingham, AL 35244 USA


Customer Service:


Phone: (877) 705-8072 Fax: (408) 865-1406

E-mail: absorbablescs@durect.com

LACTEL Technical Support:

Phone: (205) 578-5102

E-mail: absorbables@durect.com