Chemical & Physical Properties of Select Polymers

 

Chemical Properties

 

PolymerInherent Viscosity (dL/g)Crystalline Melt Transition (°C)Glass Transition Temp (°C)Solubility (at 5% w/w)Approx. Resorption (months)
50:50 DL-PLG0.55 - 0.75Amorphous45 - 501 2 3 4 5 61 - 2
65:35 DL-PLG0.55 - 0.75Amorphous45 - 501 2 3 4 5 63 - 4
75:25 DL-PLG0.55 - 0.75Amorphous50 - 551 2 3 4 5 64 - 5
85:15 DL-PLG0.55 - 0.75Amorphous50 - 551 2 3 4 5 65 - 6
DL-PLA0.55 - 0.75Amorphous50 - 601 2 3 4 5 612 - 16
L-PLA0.90 - 1.20173 - 17860 - 651 4 5>24
PCL1.00 - 1.3058-63(-65) - (-60)1 4 5>24
25:75 DL-PLCL0.70 - 0.90Amorphous(-50) - (-40)1 4 5
80:20 DL-PLCL0.70 - 0.90Amorphous17 - 231 4 5

Solvents (partial listing only) 
1 = dichloromethane 2 = tetrahydrofuran 3 = ethyl acetate 4 = chloroform 5 = hexafluoroisopropanol 6 = acetone

 

Physical Properties

 

PolymerDensity (g/mL)Tensile Strength (psi)Elongation (%)Modulus (psi)
50:50 DL-PLG1.346000 - 80003 - 102 - 4x105
65:35 DL-PLG1.306000 - 80003 - 102 - 4x105
75:25 DL-PLG1.306000 - 80003 - 102 - 4x105
85:15 DL-PLG1.276000 - 80003 - 102 - 4x105
DL-PLA1.254000 - 60003 - 102 - 4x105
L-PLA1.248000 - 120005 -104 - 6x105
PCL1.113000 - 5000300 - 5003 - 5x104
25:75 DL-PLCL1.15~1100~6005x104 - 2x105
80:20 DL-PLCL1.22~750~1506x104 - 2x105

DL-PLG = poly(DL-lactide-𝘤𝘰-glycolide), DL-PLA = poly(DL-lactide), L-PLA = poly(L-lactide), PCL= poly(ε-caprolactone)

Order Polymers

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We offer a variety of polymers and sample kits in stock for prompt delivery.

Standard Products

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A complete list of Standard Product pharmaceutical grade polymers available from LACTEL.

Custom Polymers

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If additional product optimization is required, we can provide developmental input and custom synthesis. A large percentage of our polymer business at DURECT is devoted to the development of polymers with customized characteristics.

Safety Data Sheets

The following Safety Data Sheets are saved in a format that can be viewed and printed from Acrobat Reader.