LACTEL® Absorbable Polymers for Drug Delivery
Because DURECT Corporation is engaged in employing advanced, drug delivery technologies to develop pharmaceutical products, we understand the importance of using high quality, proven excipients. Our LACTEL Absorbable Polymers have been defining polymer quality for decades, and our materials comply with the IPEC-PQG Excipient Guidelines. Our polymers are used in numerous FDA approved pharmaceutical products. In addition, we hold patents relating to the use of biodegradable polymers for improved processes in drug delivery.
Whether you are working on pharmaceuticals, nanoparticles, or drug-eluting stents, LACTEL polymers provide you with reliable materials for your formulation needs. For controlled release applications, our PLGA and PLA families of polymers are ideal. To facilitate early stage projects, these materials are available in quantities as small as ten grams in our high quality sample kits. We also offer bulk, commercial supply with the same high quality material.
Here is what researchers are saying about our materials:
“it is clear that biodegradable intrascleral implants can be easily prepared by using L-PLA (mol. wt. 61,200) which may provide a long term delivery of dexamethasone sodium phosphate inside the eye.” p. 59. Zaman N, et al. Development of L-PLA based Intrascleral Implant for Sustained Intraocular Delivery of Dexamethasone Sodium Phosphate. Stamford Journal of Pharmaceutical Sciences 2010; 2(1):56-60.
“This is the first study to show the therapeutic efficacy of the local delivery of imatinib mesylate using a polymeric delivery system.” Benny O, et al. Local Delivery of Poly Lactic-co-glycolic Acid Microspheres Containing Imatinib Mesylate Inhibits Intracranial Xenograft Glioma Growth. Clinical Cancer Research 2009; 15(4):1222.