We produce poly(lactide-co-glycolide)s, also referred to as PLGs or PLGAs, by ring-opening polymerization from lactide and glycolide monomers. Their degradation properties and long history of use in human products make PLGAs desirable for drug delivery, medical device and combination products. The LACTEL brand has been a reliable and proven source of these materials for 30 years.

Our range of PLGA incorporates monomer compositions from 50:50 up to 85:15 poly(lactide-co-glycolide). These products are offered in a range of molecular weights, as well as acid, hydroxy and ester end groups. Please refer to the table below.

For other PLGAs, please contact us to discuss your requirements. We do extensive custom synthesis for customers.  For example, we can provide block and copolymers from mPEG and PEGs.  We can perform additional purification to achieve residual monomer levels below 0.5 weight %, and manipulate other polymer characteristics to ensure the material performs to your requirements.

Our commitment to quality includes a thorough analysis of each lot of polymer, and every shipment of medical grade polymer includes a Certificate of Analysis (COA). Analyses include:

  • Identification by 1H-NMR and FTIR
  • Inherent viscosity (IV)
  • Monomer ratio
  • Residual monomer levels by 1H-NMR
  • Residual tin (from catalyst)
  • Residual solvents
  • Bioburden (total aerobes, spores, and anaerobes)
  • Pyrogens (LAL)

We maintain both Drug and Device Master Files with the FDA. All pharmaceutical grade polymer production is conducted in accordance with the International Pharmaceutical Excipients Council (IPEC) Good Manufacturing Practices Guide for Bulk Pharmaceutical Excipients, which are recognized and published in the United States Pharmacopeia. Polymers are produced in ISO 8 clean rooms with controlled temperature and humidity in our modern, well-equipped production and laboratory facilities in Birmingham, Alabama, USA.


Product No.Chemical NameEnd GroupAbbrevInherent Viscosity (IV) dL/g
Ester Terminated Polymers
B6017-150:50 Poly(DL-lactide-co-glycolide)E50:50 DL-PLG0.15 - 0.25
B6010-150:50 Poly(DL-lactide-co-glycolide)E50:50 DL-PLG0.26 - 0.54
B6010-250:50 Poly(DL-lactide-co-glycolide)E50:50 DL-PLG0.55 - 0.75
B6010-350:50 Poly(DL-lactide-co-glycolide)E50:50 DL-PLG0.76 - 0.94
B6010-450:50 Poly(DL-lactide-co-glycolide)E50:50 DL-PLG0.95 - 1.20
B6001-165:35 Poly(DL-lactide-co-glycolide)E65:35 DL-PLG 0.55 - 0.75
B6001-265:35 Poly(DL-lactide-co-glycolide)E65:35 DL-PLG0.83 - 0.93
B6007-175:25 Poly(DL-lactide-co-glycolide)E75:25 DL-PLG0.55 - 0.75
B6007-275:25 Poly(DL-lactide-co-glycolide)E75:25 DL-PLG0.80 - 1.20
B6006-185:15 Poly(DL-lactide-co-glycolide)E85:15 DL-PLG0.55 - 0.75
B6006-285:15 Poly(DL-lactide-co-glycolide)E85:15 DL-PLG0.76 - 0.85
Acid Terminated Polymers
B6013-150:50 Poly(DL-lactide-co-glycolide)A50:50 DL-PLG0.15 - 0.25
B6013-250:50 Poly(DL-lactide-co-glycolide)A50:50 DL-PLG0.55 - 0.75
B6012-475:25 Poly(DL-lactide-co-glycolide)A75:25 DL-PLG0.70 - 0.90
Glucose Star Polymer
B6131-1*Poly(DL-lactide-co-glycolide)H55:45 DL-PLG0.40 - 0.60
End GroupE - Ester Terminated, A - Acid Terminated, - Hydroxyl Terminated
*Not routinely stocked. Please call for quote and availability.

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We offer a variety of polymers and sample kits in stock for prompt delivery.

Technical Data

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Data describing characteristics of lactide, glycolide and ε-caprolactone polymers to assist you in selecting the optimal polymer for your program.